The aim of the JPND JPCOFUND-2 2021 call is to establish a number of ambitious, innovative, multi-disciplinary and multinational collaborative research projects that aim at identifying and measuring physiological effects and related biomarkers that can be linked to the development of neurodegenerative diseases, as well as enhancing the understanding of causal underlying cellular, molecular, metabolic, inflammatory or other systemic processes.
Proposals must focus on one or several of the following neurodegenerative diseases:
• Alzheimer’s disease and other dementias
• Parkinson’s disease and PD-related disorders
• Prion diseases
• Motor neuron diseases
• Huntington’s disease
• Spinocerebellar ataxia (SCA)
• Spinal muscular atrophy (SMA)
Proposals submitted under this call may include, but are not limited to, the following types of research:
• Demonstrating the relationship between early neurodegenerative processes and physiological disturbances, e.g. by analyzing existing cohorts and longitudinal data.
• Applying cutting-edge methods or technologies to improve the detection of early symptoms,e.g. by establishing innovative biomarkers and increasing the sensitivity, specificity and/or the robustness of the readouts.
• Human or animal studies to decipher the neurodegeneration-derived processes causingearly disease-specific signatures, e.g. on the neuropathological, cellular, synaptic, metabolic or inflammatory level. The use of well-characterised human cohorts’ data is encouraged.
• Using digital technologies to link recognizable symptoms to physiological changes associated to neurodegeneration, e.g. by combining clinical, neurophysiological, biochemical, imaging and psychological data.
• Relating prognostic signs of disease with real-life measurement of physiological disturbances using home-monitoring and/or wearable devices, including wireless sensors for patient monitoring.
Contact: Dr. Gaye Çetinkaya Campari
0 312 298 17 91